Monday, June 22, 2020

ISO 13485:2016 PRODUCT REALIZATION - PART 2

Hi friends!!!

In our previous blogs we have seen about CLAUSE 4, CLAUSE 5, CLAUSE 6, CLAUSE 7 of  ISO 13485:2016. Please check out for the links given below.

CLAUSE 4

CLAUSE 5

CLAUSE 6

CLAUSE 7 - PART 1

Today we are going to see remaining sub clauses of CLAUSE 7 – ISO 13485:2016.

Let’s get into the topic with a small introduction about ISO 13485:2016.

WHY ISO 

13485:2016?

ISO 13485:2016 specifies requirements for a quality management system where an organisation needs to demonstrate its ability to provide medical devices and related services that constantly meet customer and applicable regulatory requirements. Such organisations can be involved in Design & Development of Medical Device, Production, Storage  and Distribution, Installation and Servicing of Medical Device or provision for other associated activities (eg: Technical Support). 


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CLAUSE 7 PRODUCT REALIZATION

It  is divided into following sub clauses.

Clause 7.1 Planning of product realization. 
Clause 7.2 Customer related process.
Clause 7.3 Design and Development.
Clause 7.4 Purchasing.
Clause 7.5 Production and service provision.
Clause 7.6 Control of monitoring and measuring equipment.


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We have seen about CLAUSE 7.1, CLAUSE 7.2, CLAUSE 7.3 in previous blog. Let's discuss about remaining sub clauses.

CLAUSE 7.4 PURCHASING

It is divided into following sub clauses.

CLAUSE 7.4.1 Purchasing process

1. Develop procedures to control product purchases.

2. Develop supplier evaluation and selection criteria.

3. Develop supplier monitoring and re-evaluation.

4. Monitor performance of company’s suppliers.

5. Act whenever supplier fails to meet purchasing requirements.

6. Develop supplier evaluation, selection and monitoring records.

CLAUSE 7.4.2 Purchasing information

1. Plan organizations product purchases.

2. Review organizations purchase requirements before sharing them.

3. Maintain organizations purchasing documents and records.

CLAUSE 7.4.3 Verification of purchased product

1. Develop methods and activities to verify purchased product.

2. Make arrangements to verify purchased product.

3. Verify whether organizations purchased product meets purchase requirements.

4. Consider what to do when changes are made to purchased products.

5. Establish and maintain a record of purchased product verification.

CLAUSE 7.5 Production and service provision

It is divided into following sub clauses.

CLAUSE 7.5.1 Control of production and service provision

1. Plan organizations production and service provision.

2. Carry out organizations production and service provision.

3. Monitor organizations production and service provision.

4. Control organizations production and service provision.

CLAUSE 7.5.2 Cleanliness of the product

1. Identify product that organization clean prior to sterilization process.

2. Document and maintain organizations cleanliness or contamination requirements for products that you clean prior to sterilization or use.

3. Identify product that organization cannot clean prior to sterilization process.

4. Document and maintain organizations cleanliness or contamination requirements for products that you cannot clean prior to sterilization or use.

5. Identify products supplied non sterile to be cleaned before sterilization or use.

6. Document and maintain organizations cleanliness or contamination requirements for products that are supplied non sterile to be cleaned before sterilization or use.

7. Identify process agents that must be removed from products during manufacturing.

8. Document process agents that must be removed from products during manufacturing.

CLAUSE 7.5.3 Installation activities

1. This clause specifies product installation and verification requirements.

2. Establish medical device installation requirements.

3. Document organizations medical device installation requirements.

4. Establish medical device installation verification requirements.

5. Document organization medical device installation verification requirements.

CLAUSE 7.5.4 Servicing activities

1. Develop medical device servicing procedures & reference materials.

2. Document organization procedures & materials to control medical device servicing activities.

3. Use organization procedures and materials to control medical device servicing activities.

4. Maintain a record of organizations medical device servicing activities.

5. Recognize improvement opportunities and servicing complaints.

CLAUSE 7.5.5 Particular requirements for sterile medical devices

1. Develop record of organizations sterilization process parameters.

2. Record sterilization parameters for each batch of medical devices.

CLAUSE 7.5.6 Validation of processes for production & service provision

1. Develop procedures to validate production and service delivery process and software applications that could influence products & services.

2. Validate process and software application that could influence products and services.

3. Recognize process that generate output that cannot be verified by subsequent monitoring and measurement until it’s too late.

CLAUSE 7.5.7 Particular requirements for validation of process for sterilization and sterile barrier systems

1. Develop procedures used to validate process for sterilization and sterile barrier system.

2. Document procedures used to validate process for sterilization and sterile barrier system.

3. Apply procedures used to validate process for sterilization and sterile barrier system.

4. Maintain procedures used to validate process for sterilization and sterile barrier system.

CLAUSE 7.5.8 Identification

1. Develop procedures and systems to control the unique identity of medical devices.

2. Document procedures and systems to control the unique identity of medical devices.

3. Implement procedures and systems to control the unique identity of medical devices.

CLAUSE 7.5.9 Traceability

It is further divided into following sub clauses.

CLAUSE 7.5.9.1 Establish suitable product traceability procedures

1. Develop organization product traceability procedures.

2. Implement organization product traceability procedures.

3. Maintain organization product traceability procedures.

CLAUSE 7.5.9.2 Establish suitable records for implantable devices

1. Establish organizations traceability records for implantable medical devices.

2. Direct suppliers of distribution services to have distribution records.

CLAUSE 7.5.10 Customer property

1. Recognize property supplied by customers to be utilized by medical devices.

2. Verify property supplied by customers to be utilized by medical devices.

3. Protect property supplied by customers to be utilized by medical devices.

4. Keep a record of customer property that is lost, damaged or unsuitable.

5. Communicate lost, damaged or unsuitable customer property to customers.

CLAUSE 7.5.11 Preservation of product

1. Establish procedure to preserve conformity of products.

2. Document and maintain procedures to preserve conformity of products.

3. Prevent medical device damage, alteration and contamination.

4. Protect products when exposed to hazards and expected conditions.

CLAUSE 7.6 Control of monitoring and measuring equipment

1. Identify and recognize monitoring and measurement requirement.

2. Choose proper monitoring and measurement requirement.

3. Develop organizations monitoring and measurement procedures.

4. Prepare organizations calibration and verification plans & procedures.

5. Safeguard organizations monitoring and measurement equipment.

6. Establish monitoring and measurement software procedures.


Now I hope you have acquired some knowledge about CLAUSE 7 in ISO 13485:2016. We will see in detail about other CLAUSE 8 in next blog.

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